Tomographic prognostic indices for large idiopathic macular hole closure: a prospective study

Keywords

Macular hole, Optical Coherence Tomo- graphy, Macular hole closure.

Abstract

Purpose. The study aims to determine the prognostic value of spectral domain Optical Coherence Tomography (SD-OCT) in anatomical closure of large idiopathic macular hole (IMH) after surgery.

Methods. The study included 40 patients with large IMH who underwent MH surgery between January and September 2020. The inclusion criteria required patients to have a minimum of 9 months follow-up after primary MH repair surgery for a large IMH. Patients with secondary MHs or additional ocular diseases that could impact visual acuity, as well as patients with low-quality OCT images, were excluded. The patients underwent a comprehensive eye examination, color fundus photography, and OCT at baseline, 3 months, 6 months, and 9 months after surgery. The SD-OCT parameters mea- sured included minimum diameter, base diameter, macular hole height, hole form factor (HFF), macular hole index (MHI), diameter hole index (DHI), tractional hole index (THI), macular hole angle, and macular hole area index (MAI).

Results. Univariate and multivariate regression analyses demonstrated that minimum diameter, THI, and MAI were signi- ficantly correlated with anatomical success, with THI being the most important index in predicting hole closure.

Conclusion. These findings suggest that SD-OCT parameters can be useful predictors of the outcome of MH repair surgery. Further studies are recquired to study these indices.